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Incidence of Malignancy in Asymmetrical Tonsillar Enlargement  [PDF]
Jalal Al Marzooq, Jawad Abdulla, Mahmood Al Sindi
International Journal of Otolaryngology and Head & Neck Surgery (IJOHNS) , 2017, DOI: 10.4236/ijohns.2017.61002
Abstract: Objective: To determine the incidence of carcinoma in patients with asymmetrical tonsillar enlargement. Study Design: A clinical retrospective case series based on medical records of our medical complex. Results: During a two-year period, 990 patients underwent tonsillectomy at Salmaniya Medical Complex (SMC). 59 (5.9%) of those patients had asymmetrical enlargement of their tonsils, three of whom had suspicious clinical findings at presentation. The latter were found to have tonsillar malignancy on histopathological testing. Malignancy was excluded in all other specimen. Conclusions: Since the incidence of malignancy in asymmetrical tonsils is negligible in the absence of other associated risk factors, watchful waiting may be appropriate prior to any surgical intervention. Diagnostic tonsillectomy is indicated in patients with asymmetrical tonsillar enlargement with associated suspicious clinical findings, including cervical lymphadenopathy and rapid tonsillar enlargement.
Attitudes and opinions towards public littering in the Kingdom of Bahrain
Afnan Mahmood Freije,Humood Abdulla Naser,Khalil Hasan Abdulla
- , 2019, DOI: https://doi.org/10.1080/25765299.2019.1628688
Abstract: Abstract Public littering is widely recognized as an ongoing global problem with several implications on human health and the integrity of the environment. Waste management is one of the main challenges to sustainable development in the Arabian Gulf countries. Identifying factors that influence littering behaviour is critical for designing effective strategies to reduce or prevent littering. The present study investigated attitudes and opinions regarding public littering in the Kingdom of Bahrain using a questionnaire-based assessment to 408 respondents. Findings showed that around (74.26–80.54%) of the respondents indicated that they never litter in public places while those with (11.33–12.50%) admitted to litter when there is no littering facilities. The majority of the respondents (92.96%) recognized that the cleanness of public places is a shared responsibility between the governmental bodies and the public. Respondents showed positive attitude towards participating in cleaning campaigns. Age and gender were found to influence attitude and behaviour towards public littering in Bahrain. The study recommended adopting effective litter prevention project that may include public policies, technology, and educational and awareness programmes in Bahrain. Further research opportunities to draw a comprehensive picture about littering in Bahrain are also outlined
A Comparison of Wound Healing Rate Following Treatment with Aftamed and Chlorine Dioxide Gels in Streptozotocin-Induced Diabetic Rats
Fouad Al-Bayaty,Mahmood Ameen Abdulla
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/468764
Abstract: Background and Purpose. This study aimed to evaluate the wound healing activities of Aftamed and chlorine dioxide gels in streptozotocin-induced diabetic rats. Experimental Approach. Forty-eight Sprague Dawley rats were chosen for this study, divided into 4 groups. Diabetes was induced. Two-centimeter-diameter full-thickness skin excision wounds were created. Animals were topically treated twice daily. Groups 1, the diabetic control group, were treated with 0.2 mL of sterile distilled water. Group 2 served as a reference standard were treated with 0.2 mL of Intrasite gel. Groups 3 and 4 were treated with 0.2 mL of Aftamed and 0.2 mL of chlorine dioxide gels respectively. Granulation tissue was excised on the 10th day and processed for histological and biochemical analysis. The glutathione peroxidase ,superoxide dismutase activities and the malondialdehyde (MDA) levels were determined. Results. Aftamed-treated wounds exhibited significant increases in hydroxyproline, cellular proliferation, the number of blood vessels, and the level of collagen synthesis. Aftamed induced an increase in the free radical-scavenging enzyme activity and significantly reduced the lipid peroxidation levels in the wounds as measured by the reduction in the MDA level. Conclusions. This study showed that Aftamed gel is able to significantly accelerate the process of wound healing in diabetic rats.
A Concise Review on Epigenetic Regulation: Insight into Molecular Mechanisms
Shahram Golbabapour,Mahmood Ameen Abdulla,Maryam Hajrezaei
International Journal of Molecular Sciences , 2011, DOI: 10.3390/ijms12128661
Abstract: Epigenetic mechanisms are responsible for the regulation of transcription of imprinted genes and those that induce a totipotent state. Starting just after fertilization, DNA methylation pattern undergoes establishment, reestablishment and maintenance. These modifications are important for normal embryo and placental developments. Throughout life and passing to the next generation, epigenetic events establish, maintain, erase and reestablish. In the context of differentiated cell reprogramming, demethylation and activation of genes whose expressions contribute to the pluripotent state is the crux of the matter. In this review, firstly, regulatory epigenetic mechanisms related to somatic cell nuclear transfer (SCNT) reprogramming are discussed, followed by embryonic development, and placental epigenetic issues.
Bis(acetato-κ2O,O′)diphenyl(pyridine-κN)tin(IV)
Hamid Khaledi,Hapipah Mohd Ali,Mahmood A. Abdulla
Acta Crystallographica Section E , 2010, DOI: 10.1107/s1600536810007014
Abstract: The asymmetric unit of the title compound, [Sn(C6H5)2(C2H3O2)2(C5H5N)], contains two crystallography independent molecules. In both molecules, the SnIV atom is seven-coordinated in a distorted pentagonal-bipyramidal geometry with the two phenyl groups in axial positions. The two molecules differ mainly in the torsion of the phenyl and pyridine rings. The dihredral angles between the phenyl rings are 89.54 (15) and 60.11 (14)° in the two molecules while the dihedral angles between the pyridine rings and the acetate groups are 12.6 (2) and 41.77 (13)° in the two molecules.
Effect of Tinospora crispa on thioacetamide-induced liver cirrhosis in rats
Kadir Farkaad,Othman Faizah,Abdulla Mahmood,Hussan Farida
Indian Journal of Pharmacology , 2011,
Abstract: Objectives : This study was conducted to determine the effect of ethanolic extract of the dried stems of Tinospora crispa in a male rat model of hepatic fibrosis caused by the hepatotoxin, thioacetamide. Materials and Methods : The extract was gavaged daily to the rats, at doses of 100 and 200 mg/kg along with thioacetamide at a dose of 200 mg/kg twice weekly. To assess the effectivity of extract, against thioacetamide, the activity of aminotransferases (alanine aminotransferase, aspartate aminotransferase), alkaline phosphatase (AP); and bilirubin were measured, together with morphological and histopathological indices in the liver of healthy and thioacetamide-treated rats. Results : A significant increase in the activity of liver enzymes, bilirubin and G-glutamyl transferase and gross and histopathological changes were determined. Although previous in vitro study established that this extract had strong antioxidant activity, this in vivo study establishes that this extract contains hepatotoxins whose identity may be quite different from those compounds with antioxidant properties. Conclusion : The study confirms that complete reliance on data obtained using in vitro methodologies may lead to erroneous conclusions pertaining to the safety of phytopharmaceuticals.
Short Term Load Forecasting using Artificial Neural Network
Amera Ismail Melhum,Lamya abd allateef Omar,Sozan Abdulla mahmood
International Journal of Soft Computing & Engineering , 2013,
Abstract: Load forecasting helps an electric utility to make important decisions including decisions on purchasing and generating electric power, load switching, and infrastructure development. Load forecasts are extremely important for developing country like Iraq, financial institutions, and other participants in electric energy generation, transmission, distribution must be studied and took a good attention. This work analyzes and discusses a comprehensive approach for Short Term Load Forecasting (STLF) using artificial neural network. Proposed architectures were trained and tested using previous two years actual load data obtained from Duhok ELC. Control in Iraq. In this study, four ANN models are implemented and validated with reasonable accuracy on real electric load generation output data. The first and second model are to predict values of one ahead day and seven days, while the third and fourth models are also to predict values of next and seven days, concerning the amount of period of disconnected time. A forecasting performance measure such as the absolute mean error AME has been presented for each model.
Chronic Hepatitis C with Cyanosis
Jawad Khamis,Mahmood Alawainati,Muneer Abdulla,Saeed Alsaeed
- , 2019, DOI: 10.1155/2019/6586478
Abstract:
Hepatoprotective Effects of Orthosiphon stamineus Extract on Thioacetamide-Induced Liver Cirrhosis in Rats
Mohammed A. Alshawsh,Mahmood Ameen Abdulla,Salmah Ismail,Zahra A. Amin
Evidence-Based Complementary and Alternative Medicine , 2011, DOI: 10.1155/2011/103039
Abstract: Orthosiphon stamineus as medicinal plant is commonly used in Malaysia for treatment of hepatitis and jaundice; in this study, the ethanol extracts were applied to evaluate the hepatoprotective effects in a thioacetamide-induced hepatotoxic model in Sprague Dawley rats. Five groups of adult rats were arranged as follows: Group 1 (normal control group), Group 2 Thioacetamide (TAA) as positive control (hepatotoxic group), Group 3 Silymarin as a well-known standard drug (hepatoprotective group), and Groups 4 and 5 as high and low dose (treatment groups). After 60-day treatment, all rats were sacrificed. The hepatotoxic group showed a coarse granulation on the liver surface when compared to the smooth aspect observed on the liver surface of the other groups. Histopathological study confirmed the result; moreover, there was a significant increase in serum liver biochemical parameters (ALT, AST, ALP, and Bilirubin) and the level of liver Malondialdehyde (MDA), accompanied by a significant decrease in the level of total protein and Albumin in the TAA control group when compared with that of the normal group. The high-dose treatment group (200 mg/kg) significantly restored the elevated liver function enzymes near to normal. This study revealed that 200 mg/kg extracts of O. stamineus exerted a hepatoprotective effect.
The Efficacy of Gelam Honey Dressing towards Excisional Wound Healing
Mui Koon Tan,Durriyyah Sharifah Hasan Adli,Mohd Amzari Tumiran,Mahmood Ameen Abdulla,Kamaruddin Mohd Yusoff
Evidence-Based Complementary and Alternative Medicine , 2012, DOI: 10.1155/2012/805932
Abstract: Honey is one of the oldest substances used in wound management. Efficacy of Gelam honey in wound healing was evaluated in this paper. Sprague-Dawley rats were randomly divided into four groups of 24 rats each (untreated group, saline group, Intrasite Gel group, and Gelam honey group) with 2 cm by 2 cm full thickness, excisional wound created on neck area. Wounds were dressed topically according to groups. Rats were sacrificed on days 1, 5, 10, and 15 of treatments. Wounds were then processed for macroscopic and histological observations. Gelam-honey-dressed wounds healed earlier (day 13) than untreated and saline treated groups, as did wounds treated with Intrasite Gel. Honey-treated wounds exhibited less scab and only thin scar formations. Histological features demonstrated positive effects of Gelam honey on the wounds. This paper showed that Gelam honey dressing on excisional wound accelerated the process of wound healing.
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